Research

Translational Molecular Imaging and Theranostics Laboratory

Radiogenomics

Translational Molecular Imaging and Theranostics Laboratory

Radiogenomics

Radiogenomics refers to a direction of cancer research that emerges information of genomic and imaging phenotypes.
The purposes of radiogenomics are to find the association between genomic and imaging phenotypes and to develop new biomarkers for precision medicine.
We particularly focus on the molecular imaging phenotypes and genomics data to establish biomarkers which can predict the response to the specific treatments and the final clinical outcome.
These biomarkers will be utilized for the selection of the treatment strategies for each patient which is a significant goal of precision medicine.


Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue via spatial transcriptomics




Imaging of Fat Inflammation for Risk Assessment of Obesity




Risk Stratification and Response Monitoring of Cancer Patient using FDG PET/CT and PET/MR


Related Publication: PMID27175707, 26505856, 25193652, 24253568,21953008

Book Chapters: Atlas and Anatomy of PET/MRI, PET/CT and SPECT/CT

Sarker, A., Im, H. J., Cheon, G. J., Chung, H. H., Kang, K. W., Chung, J. K., ... & Lee, D. S. (2016). Prognostic implications of the SUVmax of primary tumors and metastatic lymph node measured by 18F-FDG PET in patients with uterine cervical cancer: a meta-analysis. Clinical nuclear medicine, 41(1), 34-40.





Spatial Transcriptomics-based Comprehension of Drug Distribution for Optimization of Drug Development


Related Business: https://portrai.io/services


Jeong-Bin Park, Jin-Yeong Choi, Hongyoon Choi, Hyung-Jun Im





Discovery of Biomarkers using Single Cell RNA Sequencing Analysis


Related Publication: doi.org/10.1038/s41598-021-93743-2


Lee, H., Park, J., Im, H. J., Na, K. J., & Choi, H. (2021). Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients. Scientific reports, 11(1), 1-9.