Research
Translational Molecular Imaging and Theranostics Laboratory
Nanoparticles
"Development of nanoparticle delivery platform to achieve targeted theranostics and precision medicine"
We are developing advancing delivery platforms utilizing peptides and nanoparticles (liposomes, lipid nanoparticles, virus-like particles, exosome-mimetic vesicles, etc.) for enabling both diagnosis and treatment, referred as theranostics. By leveraging the unique properties of nanoparticles and incorporating diverse materials and moieties, we address urgent challenges, such as delivering drugs to lesions through extremely narrow gaps. ur research employs innovative methodologies, including radioisotopes-based theranostics and photodynamic therapy, to deliver targeted and effective interventions for cancer. By leveraging these advanced techniques, we seek to refine diagnostic precision and treatment efficacy. Ultimately, our goal is to translate our findings into innovative and effective theranostics.
Development of Theranostic Dual-layered Au-liposome for Effective Tumor Targeting and Photothermal Therapy
Related Publication: J Nanobiotechnol 19, 262 (2021).
M1 Macrophage-Derived Exosome-Mimetic Nanovesicles with an Enhanced Cancer Targeting Ability
Related Publication: ACS Appl. Bio Mater. 2022, 5, 6, 2862–2869
Development of Spleen Targeting Liposome for Effective Treatment and Immunomodulation
Related Publication: ACS Nano 2023, 17, 5, 4327–4345
Development of Indocyanine Green/Methyl-β-cyclodextrin Complex-Loaded Liposomes for Enhanced Photothermal Cancer Therapy
Related Publication: ACS Appl. Mater. Interfaces 2024, 16, 26, 32945–32956
Development of Biocompatible Theranostic Nanomedicine
