Research
Translational Molecular Imaging and Theranostics Laboratory
Bioinformatics
Translational Molecular Imaging and Theranostics Laboratory
Radiogenomics
Radiogenomics refers to a direction of cancer research that emerges information of genomic and imaging phenotypes.
The purposes of radiogenomics are to find the association between genomic and imaging phenotypes and to develop new biomarkers for precision medicine.
We particularly focus on the molecular imaging phenotypes and genomics data to establish biomarkers which can predict the response to the specific treatments and the final clinical outcome.
These biomarkers will be utilized for the selection of the treatment strategies for each patient which is a significant goal of precision medicine.
Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue via spatial transcriptomics
Related Publication: smtd.202201091
Jeongbin Park, Jinyeong Choi, Jae Eun Lee, Hongyoon Choi, and Hyung-Jun Im* Spatial Transcriptomics-Based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue. Small Methods 2022, 6Imaging of Fat Inflammation for Risk Assessment of Obesity
Related Publication: PMID27052811, 26836629
Hyunjong Lee*, Hyung-Jun Im*, Seock-Jin Chung, Jin Chul Paeng, Gi Jeong Cheon, E. Edmund Kim, Keon Wook Kang, June-Key Chung, Dong Soo Lee, Clinicopathologic association of inflammatory activity in abdominal fat tissue on FDG-PET (In preparation)Risk Stratification and Response Monitoring of Cancer Patient using FDG PET/CT and PET/MR
Related Publication: PMID27175707, 26505856, 25193652, 24253568,21953008
Book Chapters: Atlas and Anatomy of PET/MRI, PET/CT and SPECT/CT Sarker, A., Im, H. J., Cheon, G. J., Chung, H. H., Kang, K. W., Chung, J. K., ... & Lee, D. S. (2016). Prognostic implications of the SUVmax of primary tumors and metastatic lymph node measured by 18F-FDG PET in patients with uterine cervical cancer: a meta-analysis. Clinical nuclear medicine, 41(1), 34-40.
Spatial Transcriptomics-based Comprehension of Drug Distribution for Optimization of Drug Development
Related Business: https://portrai.io/services
Jeong-Bin Park, Jin-Yeong Choi, Hongyoon Choi, Hyung-Jun ImDiscovery of Biomarkers using Single Cell RNA Sequencing Analysis
Related Publication: doi.org/10.1038/s41598-021-93743-2
Lee, H., Park, J., Im, H. J., Na, K. J., & Choi, H. (2021). Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients. Scientific reports, 11(1), 1-9.